Cerebral microangiography after hypocarbia and hypercarbia. Demonstration of deep vascular changes produced by Pa CO2 variations in the normal and ischemic brain of the rhesus monkey.

Cerebral Microangiography After Hypocarbia and Hypercarbia • Ischemic infarction was obtained in the basal ganglia and internal capsule of the Rhesus monkey by clipping the middle cerebral artery at its origin through a transorbital approach. The postmortem microvasculature was demonstrated using microtized barium (Micropaque) and soft x-ray technology. The effects on this microvasculature induced by antemortem variations in Paco,, in the normal and the acutely infarcted animal were studied. Microangiography was shown to be useful in the study of dynamic vascular changes in the deep structures of the ischemic brain. Additional